Glossary entry (derived from question below)
English term or phrase:
derail your career before you leave the station
Portuguese translation:
acabar com a sua carreira antes mesmo de ela começar
English term
Brazil
IT Specialist • M.A. in Linguistics
Native in: Portuguese (Variant: Brazilian) 
Works in: English to Portuguese, Spanish to Portuguese, Portuguese to English, and 1 more.
derail your career before you leave the station
My guess is the latter.
Refusal to shift your mindset on this matter can derail your career before you leave the station.
Tradução literal acho que não funciona, mas estou aberto a sugestões.
Obrigado!
Proposed translations
Brazil
Nothing less than high quality.
Native in: Portuguese (Variant: Brazilian)
Works in: English to Portuguese
acabar com a sua carreira antes mesmo dela começar
atrapalhar seu progresso na carreira
United States
BA in Transl., MA in ESL, 15 yrs of exp.
Native in: Portuguese
Works in: English to Portuguese, Portuguese to English, Spanish to Portuguese, and 2 more.
destruir a sua carreira antes que você caia em si / na realidade
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Note added at 8 mins (2018-07-27 18:13:20 GMT)
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derail: to cause to fail or become deflected from a purpose; reduce or delay the chances for success or development of (Merriam-Webster)
Portugal
Maria Teresa Borges de Almeida 
30+ years translating EU documents
Native in: Portuguese (Variant: European/Portugal)
Works in: English to Portuguese, French to Portuguese, Spanish to Portuguese, and 1 more.
(pode fazer) a sua carreira descarrilar antes de ganhar velocidade
dar com os burros n'água na carreira antes dela começar
Will do!
Native in: Portuguese (Variant: European/Portugal)
Works in: English to Portuguese, French to Portuguese, German to Portuguese, and 1 more.
pode prejudicar o seu percurso/carreira/progressão profissional logo à partida
Acho que o importante aqui é que se houver uma recusa em mudar de postura (Refusal to shift your mindset on this matter) as hipóteses de promoção / avanço ficam desde logo prejudicadas.
Brazil
Translating with responsability
Native in: Portuguese (Variant: Brazilian)
Works in: English to Portuguese
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