din engleză în română Medical Medical (general)

Sindromul Ehlers-Danlos

This disease is characterized by various connective tissue
changes, including skin hyperelasticity. In the more severe
types, there is a strong tendency for rupture of any of several
arteries to cause either stroke or bleeding. Rupture of the colon
or uterus has been described. There are several types of disease
based on skin, joint, or other tissue involvement. Some
are autosomal dominant, some recessive, and some X-linked
(Solomons, 2013). Their aggregate prevalence is approximately
1 in 5000 births (Prockop, 2012). Types I, II, and III are autosomally
dominant, and each accounts for about 30 percent of
cases. Type IV is uncommon but is known to predispose to preterm
delivery, ***maternal great-vessel*** rupture, postpartum bleeding,
and uterine rupture (Pepin, 2000).