English to Russian Medical Medical: Pharmaceuticals

4.2. Exclusion Criteria
Any of the following cardiovascular criteria:
Cardiac chest pain, defined as moderate pain that limits instrumental activities of daily living, ≥ 28 days before randomization
Symptomatic pulmonary embolism ≥ 28 days before randomization
Any history of acute myocardial infarction ≥ 6 months before randomization
Any history of heart failure meeting New York Heart Association Classification III or IV (Appendix 5) ≥ 6 months before randomization